Professor Swee Lay Thein

Professor of Molecular Haematology / Consultant Haematologist

E-mail:

sl.thein@kcl.ac.uk

Phone:

+44 (0) 20 7848 5443

Fax:

+44 (0) 20 7848 5444

Personal website:

http://www.kcl.ac.uk/schools/medicine/research/cancer/research/sections/haematology.html

Our research centres on the pathophysiology of the β haemoglobin disorders – the β thalassaemias and sickle cell disease – diseases that have a major global impact on public health. Both these disorders display a remarkable diversity in their clinical severity, a major ameliorating factor is the innate ability to produce fetal haemoglobin (HbF, α2γ2). Using classical twin studies, we showed that HbF levels are predominantly genetically controlled, and that almost 60% of the trait variance is accounted for by genetic factors outside the β globin locus.

Professor Swee Lay Thein is a partner of ENERCA

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